Gene information
Official symbol SELE
Official full name selectin E
Gene type protein-coding gene
Chromosome1q24.2
Alias symbolESEL; CD62E
Previous symbolELAM1; ELAM
Gene familyCD molecules; Selectins; Sushi domain containing; C-type lectin domain containing
Resources
Entrez Gene 6401
HGNC HGNC:10718
Ensembl ENSG00000007908
Vega OTTHUMG00000034851
UCSC uc001ggm.5
GO terms: 57 records
GO Description Category LogP Number of genes Detail
GO:0002090 regulation of receptor internalization GO Biological Processes -5.25557829 7 More
GO:0002092 positive regulation of receptor internalization GO Biological Processes -5.94640285 6 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002523 leukocyte migration involved in inflammatory response GO Biological Processes -8.96527714 10 More
GO:0002685 regulation of leukocyte migration GO Biological Processes -36.943236 43 More
GO:0002691 regulation of cellular extravasation GO Biological Processes -7.79276545 8 More
GO:0005901 caveola GO Cellular Components -18.8033423 19 More
GO:0005938 cell cortex GO Cellular Components -2.49954036 24 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO Biological Processes -3.60984508 9 More
GO:0007159 leukocyte cell-cell adhesion GO Biological Processes -16.8529519 16 More
GO:0007202 activation of phospholipase C activity GO Biological Processes -4.61361828 8 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0010517 regulation of phospholipase activity GO Biological Processes -7.06832255 9 More
GO:0010518 positive regulation of phospholipase activity GO Biological Processes -7.78358420 9 More
GO:0010863 positive regulation of phospholipase C activity GO Biological Processes -6.38368268 7 More
GO:0019722 calcium-mediated signaling GO Biological Processes -11.6647584 29 More
GO:0019932 second-messenger-mediated signaling GO Biological Processes -19.1717114 46 More
GO:0022407 regulation of cell-cell adhesion GO Biological Processes -32.4337382 53 More
GO:0022409 positive regulation of cell-cell adhesion GO Biological Processes -25.7751074 39 More
GO:0030029 actin filament-based process GO Biological Processes -9.62516039 61 More
GO:0030100 regulation of endocytosis GO Biological Processes -14.0757782 22 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030246 carbohydrate binding GO Molecular Functions -4.83003123 14 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031406 carboxylic acid binding GO Molecular Functions -5.96500660 23 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0034612 response to tumor necrosis factor GO Biological Processes -24.4651326 32 More
GO:0044853 plasma membrane raft GO Cellular Components -18.4542052 33 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045123 cellular extravasation GO Biological Processes -12.7826256 12 More
GO:0045785 positive regulation of cell adhesion GO Biological Processes -29.6368249 50 More
GO:0045807 positive regulation of endocytosis GO Biological Processes -11.0143833 14 More
GO:0048259 regulation of receptor-mediated endocytosis GO Biological Processes -11.3903749 15 More
GO:0048260 positive regulation of receptor-mediated endocytosis GO Biological Processes -10.1090317 11 More
GO:0048471 perinuclear region of cytoplasm GO Cellular Components -8.50169248 66 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050900 leukocyte migration GO Biological Processes -39.9164759 46 More
GO:0050901 leukocyte tethering or rolling GO Biological Processes -7.04725442 6 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0060191 regulation of lipase activity GO Biological Processes -10.2745708 13 More
GO:0060193 positive regulation of lipase activity GO Biological Processes -9.32996784 11 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0061756 leukocyte adhesion to vascular endothelial cell GO Biological Processes -8.18952769 7 More
GO:0070555 response to interleukin-1 GO Biological Processes -18.9736890 36 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0098609 cell-cell adhesion GO Biological Processes -15.7963965 69 More
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules GO Biological Processes -5.22391282 28 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:1900274 regulation of phospholipase C activity GO Biological Processes -6.23203613 7 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
GO:1903039 positive regulation of leukocyte cell-cell adhesion GO Biological Processes -20.7355312 32 More
GO:1903236 regulation of leukocyte tethering or rolling GO Biological Processes -6.04894404 5 More
GO:1903238 positive regulation of leukocyte tethering or rolling GO Biological Processes -5.22169943 4 More
GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell GO Biological Processes -9.55155535 14 More
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell GO Biological Processes -8.04419623 7 More
KEGG pathways: 7 records
KEGG Description Category LogP Number of genes Detail
hsa04514 Cell adhesion molecules KEGG Pathway -5.33785320 11 More
hsa04668 TNF signaling pathway KEGG Pathway -16.5384917 20 More
hsa04933 AGE-RAGE signaling pathway in diabetic complications KEGG Pathway -25.8646207 26 More
hsa05143 African trypanosomiasis KEGG Pathway -18.5080428 15 More
hsa05144 Malaria KEGG Pathway -31.5561809 24 More
hsa05417 Lipid and atherosclerosis KEGG Pathway -33.3876857 40 More
hsa05418 Fluid shear stress and atherosclerosis KEGG Pathway -23.1665561 27 More
Drug-Gene interaction
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Related drugs: 8 records
Related studies: 6 records
Molecular factor Omics type Application Objective MI type Reference
NM_000450.2:c.445A>C genomics myocardial infarction[diagnosis] myocardial infarction Yoshida M et al. Arterioscler Thromb Vasc Biol. 2003
E-selectin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Squadrito F et al. Int J Microcirc Clin Exp. 1995
E-selectin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Siminiak T et al. Int J Cardiol. 1997
E-selectin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Li YH et al. Am J Cardiol. 1997
E-selectin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Suefuji H et al. Am Heart J. 2000
NM_000450.2:c.98G>T genomics myocardial infarction[diagnosis] myocardial infarction Podgoreanu MV et al. Circulation. 2006
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